Article
Association between -514C-->T polymorphism of the hepatic lipase gene and coronary artery disease in a Turkish population.
Acta cardiologica - 1 Apr 2008
Gündoğdu Fuat, Gurlertop Yekta, Pirim Ibrahim, Aksakal Enbiya, Dogan Hasan, Islamoglu Yahya, Ozkan Asuman, Senocak Huseyin
Abstract excerpt
OBJECTIVE: The main function of hepatic lipase (HL) with respect to high-density lipoprotein (HDL) is hydrolysis of phospholipids and triglycerides. The -514C-->T polymorphism in the promoter region of the hepatic lipase gene affects HL activity. We aimed to investigate the association between the frequency of the -514C-->T polymorphism of hepatic lipase (PHL) and CAD in the East Anatolian region of Turkey....
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