Article
Association of lipoprotein lipase gene polymorphisms with obesity and type 2 diabetes in an Asian Indian population.
International journal of obesity (2005) - 1 Jun 2007
Radha V, Vimaleswaran K S, Ayyappa K Ashok, Mohan V
Abstract excerpt
AIMS: Lipoprotein lipase (LPL), a pivotal enzyme in lipoprotein metabolism, catalyzes the hydrolysis of triglycerides of very low-density lipoproteins and chylomicrons. Assuming that the variants in the promoter of the LPL gene may be associated with changes in lipid metabolism leading to obesity and type 2 diabetes, we examined the role of promoter variants (-T93G and -G53C) in the LPL gene in an urban South...
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