Association of hepatic lipase -514T allele with coronary artery disease and ankle-brachial index, dependence on the lipoprotein phenotype: the GENES study.

doi:10.1371/journal.pone.0067805

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Article

Association of hepatic lipase -514T allele with coronary artery disease and ankle-brachial index, dependence on the lipoprotein phenotype: the GENES study.

PloS one - 1 Jan 2013

Verdier Céline, Ruidavets Jean-Bernard, Bongard Vanina, Taraszkiewicz Dorota, Martinez Laurent O, Elbaz Meyer, Ferrières Jean, Perret Bertrand

Abstract excerpt

OBJECTIVES: Relationship between hepatic lipase (LIPC) polymorphism and coronary artery disease (CAD) has often led to contradictory results. We studied this relation by genotyping rs1800588 in the LIPC promoter in a case-control study on CAD (the GENES study). We also investigated the relationship between this polymorphism and the ankle-brachial index (ABI), which is predictive of atherosclerosis progression and...

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PMID: 23874450
DOI: 10.1371/journal.pone.0067805
PMCID: PMC3706445

Genes

CAD
LIPC

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