Article
The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects.
The Journal of clinical endocrinology and metabolism - 1 Jun 2008
Grarup Niels, Andreasen Camilla H, Andersen Mette K, Albrechtsen Anders, Sandbaek Annelli, Lauritzen Torsten, Borch-Johnsen Knut, Jørgensen Torben, Schmitz Ole, Hansen Torben, Pedersen Oluf
Abstract excerpt
CONTEXT: Hepatic lipase plays a pivotal role in the metabolism of high-density lipoprotein (HDL) and low-density lipoprotein by involvement in reverse cholesterol transport and the formation of atherogenic small dense low-density lipoprotein. OBJECTIVES: The objective was to investigate the impac...
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