The -514C>T polymorphism in the LIPC gene modifies type 2 diabetes risk through modulation of HDL-cholesterol levels in Mexicans.

doi:10.1007/s40618-020-01346-x

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Article

The -514C>T polymorphism in the LIPC gene modifies type 2 diabetes risk through modulation of HDL-cholesterol levels in Mexicans.

Journal of endocrinological investigation - 1 Mar 2021

Guerra-García M T, Moreno-Macías H, Ochoa-Guzmán A, Ordoñez-Sánchez M L, Rodríguez-Guillen R, Vázquez-Cárdenas P, Ortíz-Ortega V M, Peimbert-Torres M, Aguilar-Salinas C A, Tusié-Luna M T

Abstract excerpt

PURPOSE: Both type 2 diabetes (T2D) and low levels of high-density lipoprotein cholesterol (HDL-C) are very prevalent conditions among Mexicans. Genetic variants in the LIPC gene have been associated with both conditions. This study aimed to evaluate the association of the -514C < T (rs1800588) LIPC gene polymorphism with different metabolic traits, particularly the effects of this polymorphism on HDL-C plasma...

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PMID: 32617858
DOI: 10.1007/s40618-020-01346-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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