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Article

Genetic variation in the hepatic lipase gene is associated with combined hyperlipidemia, plasma lipid concentrations, and lipid-lowering drug response.

American heart journal - 1 Dec 2005

Cenarro Ana, Artieda Marta, Gonzalvo Carmen, Meriño-Ibarra Erardo, Arístegui Rosa, Gañán Alberto, Díaz Cristina, Sol Josep María, Pocoví Miguel, Civeira Fernando

Abstract excerpt

BACKGROUND: Combined hyperlipidemia (CHL) is a very frequent dyslipidemia, being lipid-lowering drugs often necessary in its management. Some genetic loci have been associated with CHL, and modulation of lipid-lowering treatment by genetic polymorphisms has been reported. We have investigated whe...

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Source

Identifiers

PMID: 16338252
DOI: 10.1016/j.ahj.2005.02.006

Genes

LIPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16338252-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Genetic variation in the hepatic lipase gene is associated with combined hyperlipidemia, plasma lipid concentrations, and lipid-lowering drug response.PMID 16338252Read ↗

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Common variants in the lipoprotein lipase gene, but not those in the insulin receptor substrate-1, the beta3-adrenergic receptor, and the intestinal fatty acid binding protein-2 genes, influence the lipid phenotypic expression in familial combined hyperlipidemia.Semantic proximity Read ↗

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