Article
Common adrenergic receptor polymorphisms as novel risk factors for vasospastic angina.
American heart journal - 1 Apr 2006
Park Jin-Shik, Zhang Shu-Ying, Jo Sang-Ho, Seo Jae-Bin, Li Lian, Park Kyung-Woo, Oh Byung-Hee, Park Young-Bae, Kim Hyo-Soo
Abstract excerpt
BACKGROUND: Sympathetic activity mediated by adrenergic receptors (ARs) appears to play an important role in controlling the vasomotor tone and, thus, may be associated with vasospastic angina (VA). We investigated the association of the common functional polymorphisms of the AR gene and VA. The candidates were alpha2CDel322-325, beta1Gly389Arg, beta2Arg16Gly, and beta2Gln27Glu polymorphisms. METHODS: Eighty-two...
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