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Article

Association between common genetic variants of α2A-, α2B-, and α2C-adrenergic receptors and ischemic stroke.

Clinical neurology and neurosurgery - 1 Jan 2013

Oh Seung-Hun, Min Kyung-Tae, Jeon Young-Joo, Kim Mi-Hwa, Kim Ok-Joon, Shin Byoung-Soo, Oh Doyeun, Kim Nam-Keun

Abstract excerpt

BACKGROUND: The alpha2-adrenergic receptor (α2-AR) mediates physiological responses to endogenous catecholamine, and genetic variants of α2-AR may predispose to clinical vascular diseases. We evaluated whether common genetic variants of each three subtype of alpha2-adrenergic receptor (ADRA2A, ADRA2B, and ADRA2C) were associated with ischemic stroke. METHODS: A total of 616 patients with ischemic stroke and 512...

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Identifiers

PMID: 22560155
DOI: 10.1016/j.clineuro.2012.04.002

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