Article
GLU-27 variant of beta2-adrenergic receptor polymorphisms is an independent risk factor for coronary atherosclerotic disease.
Atherosclerosis - 1 Oct 2007
Barbato Emanuele, Berger Alexandre, Delrue Leen, Van Durme Frederik, Manoharan Ganesh, Boussy Tim, Heyndrickx Guy R, De Bruyne Bernard, Ciampi Quirino, Vanderheyden Marc, Wijns William, Bartunek Jozef
Abstract excerpt
OBJECTIVE: Arg16Gly and Gln27Glu polymorphism of beta(2)-adrenergic receptors (beta 2AR) have been associated with several risk factors for coronary atherosclerotic disease (CAD). Nevertheless, conflicting data have been reported concerning their influence on CAD and cardiovascular clinical events. AIM: To investigate whether (a) beta 2AR polymorphisms are associated with CAD; and (b) the potential impact, if...
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