Article
Association between Common Genetic Variants of α2A-, α2B-, and α2C-Adrenergic Receptors and Orthostatic Hypotension.
Clinical laboratory - 1 Jan 2015
Lu Na, Yuan Ye, Piao Jinhua, Pei Fei, Sun Kai, Zheng Yang, Hui Ru-Tai
Abstract excerpt
BACKGROUND: The genetic background associated with the dysregulation of orthostatic blood pressure remains poorly understood. The sympathetic nervous system plays a pivotal role in the regulation of blood pressure, as well as in response to positional changes. The essential role of adrenergic receptors in the sympathetic nervous system prompted us to hypothesize that common genetic variants of the α2-adrenergic...
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