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EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families.

Diabetes - 1 Apr 2006

Cheyssac Claire, Dina Christian, Leprêtre Frédéric, Vasseur-Delannoy Valérie, Dechaume Aurélie, Lobbens Stéphane, Balkau Beverley, Ruiz Juan, Charpentier Guillaume, Pattou François, Joly Erik, Prentki Marc, Hansen Torben, Pedersen Oluf, Vaxillaire Martine, Froguel Philippe

Abstract excerpt

One of the most replicated loci influencing type 2 diabetes-related quantitative traits (quantitative trait loci [QTL]) is on chromosome 3q27 and modulates both type 2 diabetes-and metabolic syndrome-associated phenotypes. A QTL for type 2 diabetes age of onset (logarithm of odds [LOD] score = 3.01 at D3S3686, P = 0.0001) was identified in a set of French families. To assess genetic variation underlying both...

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Identifiers

PMID: 16567544
DOI: 10.2337/diabetes.55.04.06.db05-1298

Genes

KNG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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