Article
Coronary artery spasm and the polymorphisms of the endothelial nitric oxide synthase gene.
Circulation journal : official journal of the Japanese Circulation Society - 1 Apr 2006
Kaneda Hideaki, Taguchi Junichi, Kuwada Yukihiro, Hangaishi Misako, Aizawa Toru, Yamakado Minoru, Ogasawara Ken, Aizawa Tadanori, Ohno Minoru
Abstract excerpt
BACKGROUND: Coronary artery spasm plays an important role in the pathogenesis of vasospastic angina, and contributes to the development of several acute coronary syndromes. Endothelial nitric oxide synthase (ecNOS) catalyzes the synthesis of nitric oxide, which regulates vascular tone, and may be related to coronary vasospasm. The present study investigated whether coronary spasm is related to particular...
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