Article
Genetic risk and gene-environment interaction in coronary artery spasm in Japanese men and women.
European heart journal - 1 Jun 2004
Murase Yosuke, Yamada Yoshiji, Hirashiki Akihiro, Ichihara Sahoko, Kanda Hirofumi, Watarai Masato, Takatsu Fumimaro, Murohara Toyoaki, Yokota Mitsuhiro
Abstract excerpt
AIMS: The aim of the study was to identify genes that confer susceptibility to coronary artery spasm and clarify the interaction between genetic and environmental factors in this condition. METHODS AND RESULTS: The study population comprised 2188 Japanese individuals, including 593 subjects with coronary artery spasm (453 men, 140 women) and 1595 controls (762 men, 833 women). The genotypes for 35 polymorphisms...
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