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Article

The Glu298Asp polymorphism in the endothelial nitric oxide synthase gene is strongly associated with coronary spasm.

Coronary artery disease - 1 Jun 2003

Chang Kiyuk, Baek Sang Hong, Seung Ki-Bae, Kim Pum-Joon, Ihm Sang-Hyun, Chae Jang-Seong, Kim Jae-Hyung, Hong Soon-Jo, Choi Kyu-Bo

Abstract excerpt

BACKGROUND: Coronary spasm seems to be associated with coronary nitric oxide deficiency. OBJECTIVES: We investigated whether the Glu298Asp polymorphism in the endothelial nitric oxide synthase (eNOS) gene is a definite risk factor for coronary spasm and whether diffuse spasm involving normal-looking coronary artery correlates significantly with the Glu298Asp polymorphism, in contrast with focal spasm superimposed...

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Identifiers

PMID: 12826928
DOI: 10.1097/01.mca.0000073080.69657.71

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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