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Article

Disruption of the gene encoding the beta1-subunit of transducin in the Rd4/+ mouse.

Investigative ophthalmology & visual science - 1 Apr 2006

Kitamura Eiko, Danciger Michael, Yamashita Clyde, Rao Nagesh P, Nusinowitz Steven, Chang Bo, Farber Debora B

Abstract excerpt

PURPOSE: The Rd4/+ mouse inherits an autosomal dominant retinal degeneration that cosegregates with a large inversion spanning nearly all of mouse chromosome 4 (Chr 4). This inversion is homozygous lethal. The hypothesis for the study was that disruption of a gene at one of the two breakpoints in the Rd4 chromosome is responsible for the retinal degeneration. The purpose was to identify the disrupted gene....

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Source

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PMID: 16565360
DOI: 10.1167/iovs.05-1164

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ERG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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