Complete rescue of photoreceptor dysplasia and degeneration in transgenic retinal degeneration slow (rds) mice.

doi:10.1016/0896-6273(92)90226-4

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Article

Complete rescue of photoreceptor dysplasia and degeneration in transgenic retinal degeneration slow (rds) mice.

Neuron - 1 Jul 1992

Travis G H, Groshan K R, Lloyd M, Bok D

Abstract excerpt

retinal degeneration slow (rds) is a semidominant mutation of mice with the phenotype of abnormal development of rod and cone photoreceptors, followed by their slow degeneration. The rds gene has been putatively cloned and its novel protein product initially characterized biochemically. In the present study we undertook to correct in vivo the retinal phenotype of mice with the rds mutation. We assembled a...

Topics

Animals
Blotting, Northern
Blotting, Southern
DNA
Eye Proteins
Gene Expression
Homozygote
Intermediate Filament Proteins
Membrane Glycoproteins
Mice
Mice, Transgenic
Microscopy, Electron

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nerve Degeneration

Nerve Tissue Proteins

Peripherins

Phenotype

Photoreceptor Cells

Source

Open in PubMed

Identifiers

PMID: 1385966
DOI: 10.1016/0896-6273(92)90226-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1385966-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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