Article
The ldis1 lens mutation in RIIIS/J mice maps to chromosome 8 near cadherin 1.
Molecular vision - 23 Aug 2004
Jablonski Monica M, Lu Lu, Wang XiaoFei, Chesler Elissa J, Carps Emily, Qi Shuhua, Gu Jing, Williams Robert W
Abstract excerpt
PURPOSE: We have discovered a spontaneous and severe mutation that leads to partial or complete disruption of the lens and cataract in the RIIIS/J inbred strain of mice. The purpose of this study was to determine the mode of inheritance, specificity, and range of phenotypes using histological, ophthalmic, quantitative electron microscopic, and microarray-based methods. We also have fine-mapped the mutation, ldis1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.