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Article

A deletion in a photoreceptor-specific nuclear receptor mRNA causes retinal degeneration in the <i>rd7</i> mouse

9 May 2000

Abstract excerpt

The rd7 mouse, an animal model for hereditary retinal degeneration, has some characteristics similar to human flecked retinal disorders. Here we report the identification of a deletion in a photoreceptor-specific nuclear receptor (mPNR) mRNA that is responsible for hereditary retinal dysplasia and degeneration in the rd7 mouse. mPNR was isolated from a pool of photoreceptor-specific cDNAs originally created by...

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Identifiers

PMID: 10805811
DOI: 10.1073/pnas.97.10.5551

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Source receipt: pubmed, retrieved 7 Sept 2026.

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