Article
SUMO-1 modification of MEF2A regulates its transcriptional activity.
Journal of cellular and molecular medicine - 1 Jan 2000
Riquelme Cecilia, Barthel Kristen K B, Liu Xuedong
Abstract excerpt
Myocyte enhancer factor 2 (MEF2) transcription factors are crucial regulators controlling muscle-specific and growth factor-inducible genes. Numerous studies have reported that the activity of these transcription factors is tightly modulated by posttranslational modifications such as activation by specific phosphorylation as well as repression by class II histone deacetylases (HDACs). We hypothesized that MEF2...
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