Article
Construction and functional characterization of mutants of the bovine leukaemia virus trans-activator protein p34tax.
The Journal of general virology - 1 Oct 1991
Sakurai M, Taneda A, Nagoya H, Sekikawa K
Abstract excerpt
The p34tax protein [p38tax, p34, p38(XBL), XBL-I] of bovine leukaemia virus (BLV) activates transcription from the BLV long terminal repeat (LTR) promoter. To analyse the functional properties of this protein, inframe insertions and internal deletions were systematically introduced in a plasmid-encoded copy of the p34tax gene. The abilities of wild-type and mutant genes to activate gene expression from the LTR...
Topics
- Amino Acid Sequence
- Animals
- Cell Line
- Gene Products, tax
- Leukemia Virus, Bovine
- Molecular Sequence Data
- Mutagenesis, Insertional
- Mutation
- Plasmids
- Restriction Mapping
- Sheep
