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Article

Combinations of long terminal repeat and tax protein substitutions influence bovine leukemia virus transmission through altered viral productivity.

Microbiology spectrum - 1 Sept 2026

Murakami Hironobu, Sato Reiichiro, Uchiyama Jumpei, Sogawa Kazuyuki, Ishida Hiroho, Nagai Makoto

Abstract excerpt

Bovine leukemia virus (BLV) infection imposes a substantial economic burden on the global cattle industry. Although proviral load (PVL) in blood influences transmission, the effects of viral genetic variations, including the high viral production-associated long terminal repeat (LTR) substitution at nucleotide position 175 (LTR175), on herd-level dynamics remain unclear. This study investigated the effects of...

Read the complete abstract on PubMed

Topics

Animals
Leukemia Virus, Bovine
Cattle
Terminal Repeat Sequences
Enzootic Bovine Leukosis
Amino Acid Substitution

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Gene Products, tax

Mutation

Viral Load

Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 42505090
DOI: 10.1128/spectrum.00869-26
PMCID: PMC13532317

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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