Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutant tax protein from bovine leukemia virus with enhanced ability to activate the expression of c-fos.

Journal of virology - 1 Mar 2002

Tajima Shigeru, Aida Yoko

Abstract excerpt

Bovine leukemia virus (BLV) is the etiologic agent of enzootic bovine leukosis. We previously identified several mutants of the BLV Tax protein with an ability to transactivate transcription via the BLV enhancer that is significantly greater than that of the wild-type Tax protein. Moreover, the mutant proteins also activated other viral enhancers, such as the enhancer of human T-cell leukemia virus type 1, which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cattle
Share to Cell Line
Share to Gene Products, tax

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, fos

Share to Leukemia Virus, Bovine

Share to Promoter Regions, Genetic

Share to Proto-Oncogene Proteins c-fos

Share to Transcriptional Activation

Source

Open in PubMed Open full text

Identifiers

PMID: 11836435
DOI: 10.1128/jvi.76.5.2557-2562.2002
PMCID: PMC135937

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutant tax protein from bovine leukemia virus with enhanced ability to activate the expression of c-fos.PMID 11836435Read ↗

A mutant form of the tax protein of bovine leukemia virus (BLV), with enhanced transactivation activity, increases expression and propagation of BLV in vitro but not in vivo.Semantic proximity Read ↗

The region between amino acids 245 and 265 of the bovine leukemia virus (BLV) tax protein restricts transactivation not only via the BLV enhancer but also via other retrovirus enhancers.Semantic proximity Read ↗

Identification of bovine leukemia virus tax function associated with host cell transcription, signaling, stress response and immune response pathway by microarray-based gene expression analysis.Semantic proximity Read ↗

Transcription factor AP-4 participates in activation of bovine leukemia virus long terminal repeat by p34 Tax.Semantic proximity Read ↗

In vivo protein binding and functional analysis of cis-acting elements in the U3 region of the bovine leukemia virus long terminal repeat.Semantic proximity Read ↗

Deacetylase inhibitors and the viral transactivator TaxBLV synergistically activate bovine leukemia virus gene expression via a cAMP-responsive element- and cAMP-responsive element-binding protein-dependent mechanism.Semantic proximity Read ↗

Involvement of bovine leukemia virus in induction and inhibition of apoptosis.Semantic proximity Read ↗

Construction and functional characterization of mutants of the bovine leukaemia virus trans-activator protein p34tax.Semantic proximity Read ↗

L233P mutation in the bovine leukemia virus Tax protein has impact on annexin A3 and type I collagen secretion by host cells.Semantic proximity Read ↗

Genetic analysis of the pX region of bovine leukemia virus genotype 1 in Holstein Friesian cattle with different stages of infection.Semantic proximity Read ↗

Key elements of the human bocavirus type 1 (HBoV1) promoter and its trans-activation by NS1 protein.Semantic proximity Read ↗

Bovine papillomavirus E2 repressor mutant displays a high-copy-number phenotype and enhanced transforming activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.