Article
Population genetic estimation of the loss of genetic diversity during horizontal transmission of HIV-1.
BMC evolutionary biology - 23 Mar 2006
Edwards Charles T T, Holmes Edward C, Wilson Daniel J, Viscidi Raphael P, Abrams Elaine J, Phillips Rodney E, Drummond Alexei J
Abstract excerpt
BACKGROUND: Genetic diversity of the human immunodeficiency virus type 1 (HIV-1) population within an individual is lost during transmission to a new host. The demography of transmission is an important determinant of evolutionary dynamics, particularly the relative impact of natural selection an...
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