Article
Estimating time since infection in early homogeneous HIV-1 samples using a poisson model.
BMC bioinformatics - 25 Oct 2010
Giorgi Elena E, Funkhouser Bob, Athreya Gayathri, Perelson Alan S, Korber Bette T, Bhattacharya Tanmoy
Abstract excerpt
BACKGROUND: The occurrence of a genetic bottleneck in HIV sexual or mother-to-infant transmission has been well documented. This results in a majority of new infections being homogeneous, i.e., initiated by a single genetic strain. Early after infection, prior to the onset of the host immune resp...
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