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Article

ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating.

Nature genetics - 1 Apr 2004

Bienengraeber Martin, Olson Timothy M, Selivanov Vitaliy A, Kathmann Eva C, O'Cochlain Fearghas, Gao Fan, Karger Amy B, Ballew Jeffrey D, Hodgson Denice M, Zingman Leonid V, Pang Yuan-Ping, Alekseev Alexey E, Terzic Andre

Abstract excerpt

Stress tolerance of the heart requires high-fidelity metabolic sensing by ATP-sensitive potassium (K(ATP)) channels that adjust membrane potential-dependent functions to match cellular energetic demand. Scanning of genomic DNA from individuals with heart failure and rhythm disturbances due to idi...

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Share to ATP-Binding Cassette Transporters
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15034580
DOI: 10.1038/ng1329
PMCID: PMC1995438

Genes

ABCC9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15034580-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating.PMID 15034580Read ↗

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Cantu syndrome-associated SUR2 ( <i>ABCC9</i> ) mutations in distinct structural domains result in K <sub>ATP</sub> channel gain-of-function by differential mechanismsSemantic proximity Read ↗

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