Association of cigarette smoking and CYP1A1 polymorphisms with adenocarcinoma of the lung by grades of differentiation.

doi:10.1093/carcin/16.9.2209

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Article

Association of cigarette smoking and CYP1A1 polymorphisms with adenocarcinoma of the lung by grades of differentiation.

Carcinogenesis - 1 Sept 1995

Nakachi K, Hayashi S, Kawajiri K, Imai K

Abstract excerpt

We have previously reported on an association of genetic susceptibility to squamous cell carcinoma of the lung with two polymorphisms of the CYP1A1 gene, an MspI polymorphism and an isoleucine-valine (Ile-Val) polymorphism. We report here that the two CYP1A1 polymorphisms were associated with current or ex-smokers with adenocarcinoma of the lung. We first compared smoking status of the patients by differentiation...

Topics

Adenocarcinoma
Aged
Case-Control Studies
Cell Differentiation
Cytochrome P-450 Enzyme System
Deoxyribonuclease HpaII
Female
Genotype
Humans
Isoenzymes
Isoleucine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lung Neoplasms

Male

Middle Aged

Polymorphism, Genetic

Risk Factors

Smoking

Valine

Source

Open in PubMed

Identifiers

PMID: 7554077
DOI: 10.1093/carcin/16.9.2209

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7554077-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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