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Article

High focal adhesion kinase expression in breast carcinoma is associated with lymphovascular invasion and triple-negative phenotype

17 Oct 2014

Abstract excerpt

BACKGROUND: Focal adhesion Kinase (FAK) is a nonreceptor protein tyrosine kinase that is overexpressed in tumors and plays a significant role in tumor survival and metastasis. The purpose of the study is to perform correlation of FAK expression with patient prognostic factors using tissue microarrays (TMA) samples. METHODS: We analyzed FAK expression by immunohistochemical staining in 196 breast primary tumor...

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PMID: 25326692
DOI: 10.1186/1471-2407-14-769

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