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Article

Structural and functional features of the B-cell receptor in IgG-positive chronic lymphocytic leukemia.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2006

Potter Kathleen N, Mockridge C Ian, Neville Louise, Wheatley Isla, Schenk Michael, Orchard Jennifer, Duncombe Andrew S, Packham Graham, Stevenson Freda K

Abstract excerpt

PURPOSE: To determine the origin and relationship of the rare IgG+ variant of chronic lymphocytic leukemia (CLL) to the two common IgM+IgD+ subsets that are distinguished by expression of unmutated or mutated V(H) genes, with the former having a worse prognosis. EXPERIMENTAL DESIGN: IgG+ CLL cells were characterized using phenotypic, functional, and immunogenetic analyses. RESULTS: IgG+ CLL was phenotypically...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin M

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Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Identifiers

PMID: 16551848
DOI: 10.1158/1078-0432.CCR-05-2164

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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