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Article

The role of X inactivation and cellular mosaicism in women's health and sex-specific diseases.

JAMA - 22 Mar 2006

Migeon Barbara R

Abstract excerpt

Sex-specific manifestations of disease are most often attributed to differences in the reproductive apparatus or in life experiences. However, a good deal of sex differences in health issues have their origins in the genes on the sex chromosomes themselves and in X inactivation-the developmental program that equalizes their expression in males and females. Most females are mosaics, having a mixture of cells...

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Identifiers

PMID: 16551715
DOI: 10.1001/jama.295.12.1428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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