Why females are mosaics, X-chromosome inactivation, and sex differences in disease.

Abstract excerpt

At every age, males have a higher risk of mortality than do females. This sex difference is most often attributed to the usual suspects: differences in hormones and life experiences. However, the fact that XY males have only one X chromosome undoubtedly contributes to this vulnerability, as any mutation that affects a gene on their X chromosome will affect their only copy of that gene. On the other hand, cellular...

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• Share to Chromosomes, Human, X
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• Share to Genetic Predisposition to Disease