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Article

Increase of the spontaneous mutation rate in a long-term experiment with Drosophila melanogaster.

Genetics - 1 May 2006

Avila Victoria, Chavarrías David, Sánchez Enrique, Manrique Antonio, López-Fanjul Carlos, García-Dorado Aurora

Abstract excerpt

In a previous experiment, the effect of 255 generations of mutation accumulation (MA) on the second chromosome viability of Drosophila melanogaster was studied using 200 full-sib MA1 lines and a large C1 control, both derived from a genetically homogeneous base population. At generation 265, one of those MA1 lines was expanded to start 150 new full-sib MA2 lines and a new C2 large control. After 46 generations,...

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Identifiers

PMID: 16547099
DOI: 10.1534/genetics.106.056200
PMCID: PMC1461422

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