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Article

Rapid mutational declines of viability in Drosophila.

Genetical research - 1 Feb 2001

Fry J D

Abstract excerpt

High rates of mildly deleterious mutation could cause the extinction of small populations, reduce neutral genetic variation and provide an evolutionary advantage for sex. In the first attempts to estimate the rate of mildly deleterious mutation, Mukai and Ohnishi allowed spontaneous mutations to accumulate on D. melanogaster second chromosomes shielded from recombination and selection. Viability of the shielded...

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PMID: 11279830
DOI: 10.1017/s0016672300004882

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Source receipt: pubmed, retrieved 7 Sept 2026.

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