Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Accumulation of deleterious mutations: additional Drosophila melanogaster estimates and a simulation of the effects of selection.

Evolution; international journal of organic evolution - 1 Jun 2002

Caballero A, Cusi E, García C, García-Dorado A

Abstract excerpt

We report an assay of egg-to-adult viability in full-sibling mutation accumulation (MA) lines derived from a completely homozygous population of Drosophila melanogaster and maintained for 210 generations. A simultaneous evaluation was also made of a large population derived from the same origin and maintained as a control for the same period. We also present computer simulations to explore the possible decline in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Mutation

Share to Reproduction

Share to Selection, Genetic

Source

Identifiers

PMID: 12144016
DOI: 10.1111/j.0014-3820.2002.tb01428.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Accumulation of deleterious mutations: additional Drosophila melanogaster estimates and a simulation of the effects of selection.PMID 12144016Read ↗

New estimates of the rates and effects of mildly deleterious mutation in Drosophila melanogaster.Semantic proximity Read ↗

Increase of the spontaneous mutation rate in a long-term experiment with Drosophila melanogaster.Semantic proximity Read ↗

On the rate and linearity of viability declines in Drosophila mutation-accumulation experiments: genomic mutation rates and synergistic epistasis revisited.Semantic proximity Read ↗

The mutation rate and the distribution of mutational effects of viability and fitness in Drosophila melanogaster.Semantic proximity Read ↗

Rapid mutational declines of viability in Drosophila.Semantic proximity Read ↗

The mutational rate of Drosophila viability decline: tinkering with old data.Semantic proximity Read ↗

Environment dependence of mutational parameters for viability in Drosophila melanogaster.Semantic proximity Read ↗

The rate of mutation and the homozygous and heterozygous mutational effects for competitive viability: a long-term experiment with Drosophila melanogaster.Semantic proximity Read ↗

Population genetics: surviving under mutation pressure.Semantic proximity Read ↗

Genomic mutation rates for lifetime reproductive output and lifespan in Caenorhabditis elegans.Semantic proximity Read ↗

On the genetic parameter determining the efficiency of purging: an estimate for Drosophila egg-to-pupae viability.Semantic proximity Read ↗

Mutation-selection balance accounting for genetic variation for viability in Drosophila melanogaster as deduced from an inbreeding and artificial selection experiment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.