Article

A transgene harboring the human Glucose Transporter1 (GLUT1) gene locus ameliorates disease in GLUT1 deficiency syndrome model mice

2025-04-06

Abstract excerpt

Proper brain function relies on an adequate supply of energy – mainly glucose – to power neuronal activity. Delivery of this nutrient to the neuropil is mediated by the Glucose Transporter1 (GLUT1) protein. Perturbing glucose supply to the brain is profoundly damaging and exemplified by the neurodevelopmental disorder, GLUT1 deficiency syndrome (GLUT1DS). Resulting from haploinsufficiency of the SLC2A1 (GLUT1) ge...

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Literature Corpus work: 9f9bea32-ad5b-5bd2-8847-86544d4966fa
DOI: 10.1101/2025.04.05.647372

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