Article
Drosophila oocyte polarity and cytoskeleton organization require regulation of Ik2 activity by Spn-F and Javelin-like.
Molecular and cellular biology - 1 Nov 2013
Amsalem Simha, Bakrhat Anna, Otani Tetsuhisa, Hayashi Shigeo, Goldstein Bareket, Abdu Uri
Abstract excerpt
The Drosophila melanogaster Spn-F, Ik2, and Javelin-like (Jvl) proteins interact to regulate oocyte mRNA localization and cytoskeleton organization. However, the mechanism by which these proteins interact remains unclear. Using antibodies to activated Ik2, we showed that this protein is found at the region of oocyte and follicle cell where microtubule minus ends are enriched. We demonstrate that germ line Ik2...
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