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Article

The mago nashi gene is required for the polarisation of the oocyte and the formation of perpendicular axes in Drosophila.

Current biology : CB - 1 Jul 1997

Micklem D R, Dasgupta R, Elliott H, Gergely F, Davidson C, Brand A, González-Reyes A, St Johnston D

Abstract excerpt

BACKGROUND: Drosophila axis formation requires a series of inductive interactions between the oocyte and the somatic follicle cells. Early in oogenesis, Gurken protein, a member of the transforming growth factor alpha family, is produced by the oocyte to induce the adiacent follicle cells to adopt a posterior cell fate. These cells subsequently send an unidentified signal back to the oocyte to induce the...

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PMID: 9210377
DOI: 10.1016/s0960-9822(06)00218-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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The mago nashi gene is required for the polarisation of the oocyte and the formation of perpendicular axes in Drosophila.PMID 9210377Read ↗

mago nashi mediates the posterior follicle cell-to-oocyte signal to organize axis formation in Drosophila.Semantic proximity Read ↗

Oocyte determination and the origin of polarity in Drosophila: the role of the spindle genes.Semantic proximity Read ↗

The RNA-binding protein Tsunagi interacts with Mago Nashi to establish polarity and localize oskar mRNA during Drosophila oogenesis.Semantic proximity Read ↗

The mago nashi locus encodes an essential product required for germ plasm assembly in Drosophila.Semantic proximity Read ↗

maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA.Semantic proximity Read ↗

cornichon and the EGF receptor signaling process are necessary for both anterior-posterior and dorsal-ventral pattern formation in Drosophila.Semantic proximity Read ↗

spn-F encodes a novel protein that affects oocyte patterning and bristle morphology in Drosophila.Semantic proximity Read ↗

Polarization of both major body axes in Drosophila by gurken-torpedo signalling.Semantic proximity Read ↗

The identification of novel genes required for Drosophila anteroposterior axis formation in a germline clone screen using GFP-Staufen.Semantic proximity Read ↗

Combined activities of Gurken and decapentaplegic specify dorsal chorion structures of the Drosophila egg.Semantic proximity Read ↗

Drosophila Y14 shuttles to the posterior of the oocyte and is required for oskar mRNA transport.Semantic proximity Read ↗

Barentsz is essential for the posterior localization of oskar mRNA and colocalizes with it to the posterior pole.Semantic proximity Read ↗

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