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Article

Polymorphisms of the FAS and FAS ligand genes associated with risk of cutaneous malignant melanoma.

Pharmacogenetics and genomics - 1 Apr 2006

Li Chunying, Larson Derek, Zhang Zhengdong, Liu Zhensheng, Strom Sara S, Gershenwald Jeffrey E, Prieto Victor G, Lee Jeffrey E, Ross Merrick I, Mansfield Paul F, Cormier Janice N, Duvic Madeleine, Grimm Elizabeth A, Wei Qingyi

Abstract excerpt

The FAS/FAS ligand (FASLG) system has a key role in regulating cell growth and thus tumorigenesis. Functional promoter polymorphisms of the FAS and FASLG genes alter the transcriptional activities, but no published study has investigated the role of these polymorphisms in the etiology of cutaneous malignant melanoma (CMM). In a hospital-based, case-control study of 602 non-Hispanic white CMM patients and 603...

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Source

Identifiers

PMID: 16538172
DOI: 10.1097/01.fpc.0000199501.54466.de

Genes

FAS
FASLG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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