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Article

Functional polymorphisms of the FAS gene associated with risk of vitiligo in Chinese populations: a case-control analysis.

The Journal of investigative dermatology - 1 Dec 2008

Li Miao, Sun Dongjie, Li Chunying, Zhang Zhengdong, Gao Lin, Li Kai, Li Hong, Gao Tianwen

Abstract excerpt

The FAS/FASLG system plays a key role in regulating apoptosis. Previous findings have shown that CD4-dependent destruction of melanocytes is partially inhibited by blocking FAS-FASLG interactions in autoimmune vitiligo. Functional polymorphisms of the FAS and FASLG genes can alter their transcrip...

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Source

Identifiers

PMID: 18548110
DOI: 10.1038/jid.2008.161

Genes

FAS
FASLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18548110-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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