Article
Comprehensive pathway-based interrogation of genetic variations in the nucleotide excision DNA repair pathway and risk of bladder cancer.
Cancer - 1 Jan 2012
Xing Jinliang, Dinney Colin P, Shete Sanjay, Huang Maosheng, Hildebrandt Michelle A, Chen Zhinan, Gu Jian
Abstract excerpt
BACKGROUND: Growing evidence suggests that single nucleotide polymorphisms (SNPs) in nucleotide excision repair (NER) pathway genes play an important role in bladder cancer etiology. However, only a limited number of genes and variations in this pathway have been evaluated to date. METHODS: In this study, the authors applied a comprehensive pathway-based approach to assess the effects of 207 tagging and...
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