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Article

Pedigree and genetic analysis of a novel mutation carrier patient suffering from hereditary nonpolyposis colorectal cancer.

World journal of gastroenterology - 28 Feb 2006

Tanyi Miklós, Olasz Judith, Lukács Géza, Csuka Orsolya, Tóth László, Szentirmay Zoltán, Ress Zsuzsa, Barta Zsolt, Tanyi János L, Damjanovich László

Abstract excerpt

AIM: To screen a suspected Hungarian HNPCC family to find specific mutations and to evaluate their effect on the presentation of the disease. METHODS: The family was identified by applying the Amsterdam and Bethesda Criteria. Immunohistochemistry was performed, and DNA samples isolated from tumor tissue were evaluated for microsatellite instability. The identification of possible mutations was carried out by...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Share to DNA, Neoplasm

Share to MutL Protein Homolog 1

Share to MutS Homolog 2 Protein

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Share to Polymorphism, Single-Stranded Conformational

Source

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Identifiers

PMID: 16534870
DOI: 10.3748/wjg.v12.i8.1192
PMCID: PMC4124428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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