Article
Inflammatory bowel disease: Crohn's disease and the success of NODern genetics.
Clinical and investigative medicine. Medecine clinique et experimentale - 1 Dec 2003
Newman Bill, Siminovitch Katherine
Abstract excerpt
The inflammatory bowel diseases (IBDs), Crohn's disease and ulcerative colitis, are multifactorial in etiology, but a major causative role for genetic factors has long been recognized. Recent advances in genetic technologies have made dissection of the genes underlying common diseases possible; consequently, there is an emerging understanding of the inherited factors that predispose to IBD. In this review, we...
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