Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DLG5 variants in inflammatory bowel disease.

The American journal of gastroenterology - 1 Apr 2006

Büning Carsten, Geerdts Lars, Fiedler Thomas, Gentz Enno, Pitre Ghyslaine, Reuter Wolf, Luck Werner, Buhner Sabine, Molnar Tomas, Nagy Ferenc, Lonovics Janos, Dignass Axel, Landt Olfert, Nickel Renate, Genschel Janine, Lochs Herbert, Schmidt Hartmut H-J, Witt Heiko

Abstract excerpt

OBJECTIVES: Genetic variants within DLG5 were recently reported to be associated with inflammatory bowel disease (IBD). The aim of our study was to test for allelic and haplotype associations of six DLG5 variants in 668 IBD patients from two European populations. Furthermore, we evaluated whether DLG5 variants alter gastrointestinal permeability in Crohn's disease (CD). METHODS: Six DLG5 variants (p.R30Q,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colitis, Ulcerative
Share to Crohn Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germany

Share to Hungary

Share to Intestinal Mucosa

Share to Nod2 Signaling Adaptor Protein

Share to Permeability

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 16494592
DOI: 10.1111/j.1572-0241.2006.00431.x

Genes

DLG5

Variants

rs2289308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DLG5 variants in inflammatory bowel disease.PMID 16494592Read ↗

Investigation of association of the DLG5 gene with phenotypes of inflammatory bowel disease in the British population.Semantic proximity Read ↗

DLG5 R30Q is not associated with IBD in Hungarian IBD patients but predicts clinical response to steroids in Crohn's disease.Semantic proximity Read ↗

Role of CARD15, DLG5 and OCTN genes polymorphisms in children with inflammatory bowel diseases.Semantic proximity Read ↗

DLG5 variants do not influence susceptibility to inflammatory bowel disease in the Scottish population.Semantic proximity Read ↗

Relationship between CARD15, SLC22A4/5, and DLG5 polymorphisms and early-onset inflammatory bowel diseases: an Italian multicentric study.Semantic proximity Read ↗

Association of DLG5 variants with inflammatory bowel disease in the New Zealand Caucasian population and meta-analysis of the DLG5 R30Q variant.Semantic proximity Read ↗

Extreme heterogeneity in CARD15 and DLG5 Crohn disease-associated polymorphisms between German and Norwegian populations.Semantic proximity Read ↗

Contribution of IBD5 locus to clinical features of IBD patients.Semantic proximity Read ↗

Genetic variants in TNF-alpha but not DLG5 are associated with inflammatory bowel disease in a large United Kingdom cohort.Semantic proximity Read ↗

The R30Q DLG5 variant is not associated with celiac disease or inflammatory bowel disease in the Spanish population.Semantic proximity Read ↗

Genetic susceptibility has a more important role in pediatric-onset Crohn's disease than in adult-onset Crohn's disease.Semantic proximity Read ↗

Genetic variation in DLG5 is associated with inflammatory bowel disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.