Article
Cytotoxic T lymphocyte antigen-4 promoter variants in breast cancer.
Cancer genetics and cytogenetics - 1 Mar 2006
Erfani N, Razmkhah M, Talei A R, Pezeshki A M, Doroudchi M, Monabati A, Ghaderi A
Abstract excerpt
CTLA4 is a coinhibitory molecule expressed mainly on activated T lymphocytes. To test the putative involvement of CTLA-4 in inhibitory state of immunity to breast cancer, we genotyped 283 patients and 245 healthy control subjects for -1722 T/C, -1661 A/G, and -318 C/T single nucleotide polymorphisms in the promoter region of the CTLA4 gene. There were no significant differences in genotype, allele, or haplotype...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
