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Article

Cytotoxic T-lymphocyte antigen 4 polymorphisms and breast cancer susceptibility: Evidence from a meta-analysis.

Journal of the Chinese Medical Association : JCMA - 1 Feb 2023

Chang Hao-Yun, Liu Chao-Yu, Lo Yen-Li, Chiou Shih-Hwa, Lu Kai-Hsi, Lee Ming-Cheng, Wang Yuan-Hung

Abstract excerpt

BACKGROUND: Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is an immune checkpoint and regulates the immune function of T cells. However, previous findings regarding the association of CTLA-4 polymorphisms and breast cancer remain inconclusive. Therefore, we performed a meta-analysis to investigate the potential effects of five polymorphisms (-1722 T/C, -1661 A/G -318 C/T, +49 A/G, and CT60 A/G) in the CTLA-4 gene on...

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PMID: 36652567
DOI: 10.1097/JCMA.0000000000000851

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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