High-degree tumor budding and podia-formation in sporadic colorectal carcinomas with K-ras gene mutations.

doi:10.1016/j.humpath.2007.04.002

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Article

High-degree tumor budding and podia-formation in sporadic colorectal carcinomas with K-ras gene mutations.

Human pathology - 1 Nov 2007

Prall Friedrich, Ostwald Christiane

Abstract excerpt

In vitro ras activation enhances the epithelial-mesenchymal transition of colorectal carcinoma cells. But ras effects are known to be highly dependent on cell types and the tissue context. Therefore, this study was made to test the hypothesis that in clinical colorectal carcinoma specimens, aggre...

Topics

Adult
Aged
Aged, 80 and over
Colorectal Neoplasms
Female
Genes, ras
Humans
Male
Middle Aged
Mutation

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