Article
Hematopoietic chimerism monitoring based on STRs: quantitative platform performance on sequential samples.
Journal of biomolecular techniques : JBT - 1 Dec 2005
Kristt Don, Israeli Moshe, Narinski Ronit, Or Hagit, Yaniv I, Stein Jerry, Klein Tirza
Abstract excerpt
Hematopoietic stem cell transplantation (HSCT) creates a donor-recipient cellular chimerism in the patient, which is quantitatively assayed from peripheral blood based on STR-DNA. Since chimerism values often vary across a patient's samples, it is important to determine to what extent this variability reflects technical aspects of platform performance. This issue is systematically assessed in the current study...
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