Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative monitoring of multi-donor chimerism: a systematic, validated framework for routine analysis.

Bone marrow transplantation - 1 Jan 2010

Kristt D, Gesundheit B, Stein J, Shapira M Y, Or R, Amar A, Yaniv I, Garty B, Itah R, Israeli M, Klein T

Abstract excerpt

Despite therapeutic advantages, double-donor (DD) HSCTs present technical problems for molecular chimerism (CHM) monitoring. These DD chimeras contain three matched DNAs, so that the genomes of donor(s) and recipient often share the same alleles. In the STR assay, shared recipient/donor alleles are common and have identical physico-chemical properties. As a consequence of the latter, they co-migrate in the same...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Electrophoresis
Share to Hematopoietic Stem Cell Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Minisatellite Repeats

Share to Polymerase Chain Reaction

Share to Reproducibility of Results

Share to Tandem Repeat Sequences

Share to Tissue Donors

Share to Transplantation Chimera

Source

Identifiers

PMID: 19503109
DOI: 10.1038/bmt.2009.120

Genes

CHM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative monitoring of multi-donor chimerism: a systematic, validated framework for routine analysis.PMID 19503109Read ↗

Hematopoietic chimerism monitoring based on STRs: quantitative platform performance on sequential samples.Semantic proximity Read ↗

Evaluation of STR informativity for chimerism testing – comparative analysis of 27 STR systems in 203 matched related donor recipient pairsSemantic proximity Read ↗

Chimerism Monitoring Techniques after Hematopoietic Stem Cell Transplantation: An Overview of the Last 15 Years of InnovationsSemantic proximity Read ↗

Validation of next-generation sequencing-based chimerism testing for accurate detection and monitoring of engraftment in hematopoietic stem cell transplantationSemantic proximity Read ↗

Digital PCR Panel for Sensitive Hematopoietic Chimerism Quantification after Allogeneic Stem Cell TransplantationSemantic proximity Read ↗

Evaluation of Chimerism Testing by Next-Generation Sequencing Using Insertion/Deletion Markers: Analytical Validation and Examples of Clinical Utilization.Semantic proximity Read ↗

A technical application of quantitative next generation sequencing for chimerism evaluation.Semantic proximity Read ↗

Performance characteristics of chimerism testing by next generation sequencing.Semantic proximity Read ↗

Recent advances in quantitative chimerism analysis.Semantic proximity Read ↗

Chimerism Assay Using Single Nucleotide Polymorphisms Adjacent and in Linkage-Disequilibrium Enables Sensitive Disease Relapse Monitoring after Hematopoietic Stem-Cell Transplantation.Semantic proximity Read ↗

Performance Characteristics of Next-Generation Sequencing-Based Engraftment Monitoring and Microchimerism Detection in Allogeneic Hematopoietic Cell Transplantation: A Practical Approach for Clinical Assay Validation.Semantic proximity Read ↗

Earlier relapse detection after allogeneic haematopoietic stem cell transplantation by chimerism assays: Digital PCR versus quantitative real-time PCR of insertion/deletion polymorphismsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.