Article
Estimating the number of coding mutations in genotypic- and phenotypic-driven N-ethyl-N-nitrosourea (ENU) screens.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 2006
Keays David A, Clark Taane G, Flint Jonathan
Abstract excerpt
N-ethyl-N-nitrosourea (ENU) is a widely used mutagen in genotypic and phenotypic screens aimed at elucidating gene function. The high rate at which ENU induces point mutations raises the possibility that an observed phenotype may be to the result of another unidentified linked mutation. This arti...
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