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Article

The gamma-parvin-integrin-linked kinase complex is critically involved in leukocyte-substrate interaction.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2006

Yoshimi Ryusuke, Yamaji Satoshi, Suzuki Atsushi, Mishima Wataru, Okamura Mayumi, Obana Takashi, Matsuda Chie, Miwa Yoshihiro, Ohno Shigeo, Ishigatsubo Yoshiaki

Abstract excerpt

Leukocyte extravasation is an important step of inflammation, in which integrins have been demonstrated to play an essential role by mediating the interaction of leukocytes with the vascular endothelium and the subendothelial extracellular matrix. Previously, we identified an integrin-linked kinase (ILK)-binding protein affixin (beta-parvin), which links initial integrin signals to rapid actin reorganization, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16517730
DOI: 10.4049/jimmunol.176.6.3611

Genes

ILK
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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