Interleukin-18 gene 105A/C genetic polymorphism is associated with the susceptibility of Kawasaki disease.

doi:10.1002/jcla.20292

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Article

Interleukin-18 gene 105A/C genetic polymorphism is associated with the susceptibility of Kawasaki disease.

Journal of clinical laboratory analysis - 1 Jan 2009

Chen Shih-Yin, Wan Lei, Huang Yu-Chuen, Sheu Jim Jinn-Chyuan, Lan Yu-Ching, Lai Chih-Ho, Lin Cheng-Wen, Chang Jeng Sheng, Tsai Yuhsin, Liu Shih-Ping, Lin Ying-Ju, Tsai Fuu-Jen

Abstract excerpt

Interleukin-18 (IL-18)-656T/G, -607A/C, and -137C/G promoter polymorphisms had been reported associated with Kawasaki disease (KD). An IL-18 genetic A/C polymorphism at coding position 105 (rs549908) has been linked with asthma, rheumatoid, and systemic lupus erythematosus. We tested a hypothesis that the IL-18 105A/C genetic polymorphism confers KD susceptibility. Study participants were Taiwanese KD patients...

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PMID: 19288449
DOI: 10.1002/jcla.20292
PMCID: PMC6649070

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